Dec 30 2007

i-Snake to Transform Modern Day Surgery

Tag: BBC, Healthcare, Medical, Research, Robots, TechLuver, UK, UniversitiesJack @ 6:38 AM

i-Snake to Transform Modern Day SurgeryLondon — BBC News reports on Experts developing a flexible surgical robot, known as the i-Snake, which they say could revolutionize keyhole surgery. It could enable surgeons to do complex procedures previously possible only through more invasive techniques.

A team at Imperial College London has been granted £2.1 million for the work.

The i-Snake, a long tube housing special motors, sensors and imaging tools, has the potential to allow complex heart and bowel operations to be carried out without making an incision.

According to the research team, the i-Snake could also be used to detect problems in the gut and bowel by acting as the surgeon’s hands and eyes in hard to reach places inside the body. The Imperial College team, which includes health minister and surgeon Lord Ara Darzi, will test the device in the laboratory first, before using it on patients.

Lord Darzi said i-Snake could be in use within five years, resulting in cheaper operations and faster recovery times for patients. The robot’s diameter will vary between that of a 5p and a 10p piece and it will contain fibre-optic cables to relay information to the surgeon.

“The unrivalled imaging and sensing capabilities coupled with the accessibility and sensitivity of i-Snake will enable more complex diagnostic and therapeutic procedures than are currently possible, BBC quoted Lord Darzi, as saying. More at BBC News.


Dec 19 2007

Stanford’s Nanowire Battery Holds 10 Times the Charge of Existing Ones

Photos taken by a scanning electron microscope of silicon nanowires before (left) and after (right) absorbing lithium. Both photos were taken at the same magnification : Image Credit: Stanford News Service

Stanford Report — Dec 18,`07 — Dan Stober writes an in-depth article on Stanford’s nanowire battery at Stanford news service.

Stanford researchers have found a way to use silicon nanowires to reinvent the rechargeable lithium-ion batteries that power laptops, iPods, video cameras, cell phones, and countless other devices.

The new version, developed through research led by Yi Cui, assistant professor of materials science and engineering, produces 10 times the amount of electricity of existing lithium-ion, known as Li-ion, batteries. A laptop that now runs on battery for two hours could operate for 20 hours, a boon to ocean-hopping business travelers.

“It’s not a small improvement,” Cui said. “It’s a revolutionary development.”

The breakthrough is described in a paper, “High-performance lithium battery anodes using silicon nanowires,” published online Dec. 16 in Nature Nanotechnology, written by Cui, his graduate chemistry student Candace Chan and five others.

The greatly expanded storage capacity could make Li-ion batteries attractive to electric car manufacturers. Cui suggested that they could also be used in homes or offices to store electricity generated by rooftop solar panels.

“Given the mature infrastructure behind silicon, this new technology can be pushed to real life quickly,” Cui said.

The electrical storage capacity of a Li-ion battery is limited by how much lithium can be held in the battery’s anode, which is typically made of carbon. Silicon has a much higher capacity than carbon, but also has a drawback.

Silicon placed in a battery swells as it absorbs positively charged lithium atoms during charging, then shrinks during use (i.e., when playing your iPod) as the lithium is drawn out of the silicon. This expand/shrink cycle typically causes the silicon (often in the form of particles or a thin film) to pulverize, degrading the performance of the battery.

Cui’s battery gets around this problem with nanotechnology. The lithium is stored in a forest of tiny silicon nanowires, each with a diameter one-thousandth the thickness of a sheet of paper. The nanowires inflate four times their normal size as they soak up lithium. But, unlike other silicon shapes, they do not fracture.

Research on silicon in batteries began three decades ago. Chan explained: “The people kind of gave up on it because the capacity wasn’t high enough and the cycle life wasn’t good enough. And it was just because of the shape they were using. It was just too big, and they couldn’t undergo the volume changes.”

Then, along came silicon nanowires. “We just kind of put them together,” Chan said.

For their experiments, Chan grew the nanowires on a stainless steel substrate, providing an excellent electrical connection. “It was a fantastic moment when Candace told me it was working,” Cui said.

Cui said that a patent application has been filed. He is considering formation of a company or an agreement with a battery manufacturer. Manufacturing the nanowire batteries would require “one or two different steps, but the process can certainly be scaled up,” he added. “It’s a well understood process.” More at Stanford.edu


Dec 17 2007

Global Action Call to Save Coral Reefs

Global Action Call to Save Coral Reefs

Eminent coral scientists have given world leaders more reason to act urgently against climate change, by producing a new report that warns coral reefs will disappear within decades if atmospheric CO2 levels continue to rise.

Their paper, published on Dec14, in the prestigious Science magazine, is the most compelling scientific case yet that unchecked global warming will be a disaster for coral reefs and the 100 million people and one million species depending on them.

CO2 concentration in the earth’s atmosphere is currently 380 parts per million (ppm) but the authors say if future emissions exceed 450ppm we risk losing reefs.

“This is a very ambitious target and should represent yet another reality check for world leaders meeting in Bali,” lead author UQ Professor Ove Hoegh-Guldberg said.

The study has found serious consequences follow on from even small increases in CO2.

“The warmer and more acidic oceans caused by the rise of CO2 from the burning of fossil fuels threaten to destroy coral dominated reef ecosystems, exposing people to flooding, coastal erosion and the loss of food and income from reef-based fisheries and tourism,” Professor Hoegh-Guldberg said.

“Increased CO2 not only warms the climate but also dissolves in sea water making it more acidic. “This, in turn, decreases the ability of corals to produce calcium carbonate, which is what the all-important framework of coral reefs is made of.”More at the University of Queensland.


Dec 16 2007

Arctic Summer Melting in 2007 Set New Records

ICE BUOY - MEASURING SEA-ICE THICKNESS IN THE ARCTICDisappearance of Old Ice, 1982–2007

San Francisco, Calif — Arctic sea ice shrank drastically this summer, reaching a record low, largely because warm ocean currents ate away at the base of the ice sheet, new research says. The arctic ice cap melted at an unprecedented rate in mid-2007, losing an area of ice the size of the state of Alaska, US scientists said at a conference this week.

“The average rate of loss of sea ice every summer year to year up to 2006 was equal to an area the size of West Virginia,” or about 62,800 square kilometers (24,250 square miles), said Michael Steele, the senior oceanographer at the University of Washington in Seattle.

However the decrease in ice between 2006 and 2007 “was almost equivalent to the area of Alaska,” or some 1.7 million kilometers (more than 663,000 square miles), Steele further said.

“It was a huge retreat,” said Steele, one of the researchers who discussed the subject at the annual American Geophysical Union (AGU) conference in San Francisco, California.

At the fall meeting of the American Geophysical Union (AGU) in San Francisco, some scientists argued yesterday that the end of the perennial ice is near.

“If this trend persists, the Arctic would be ice-free [in the summer] by 2013,” said Wieslaw Maslowski of the Naval Postgraduate School in Monterey, California. The researchers told a meeting of the American Geophysical Union that some of the observations had been astonishing.

“The further you go down this path, the harder it is to get back,” observed Don Perovich from the US Army Cold Regions Research and Engineering Laboratory. “Things could come back, but basically it’s the fourth quarter and we’re down two touchdowns,” he said, using an analogy from American football.

The big thin
The extent of the sea ice cover fell to a record minimum in September of 4.13 million sq km, beating the previous low mark, set in 2005, by 23%. This was well publicised at the time, but some of the other “Arctic numbers” have not been so widely reported. Scientists say they demonstrate the step changes in environmental conditions in the northern polar region.

Minimum_Ice_Extent_US_NSIDCWarmth from below
A big driver behind the melt is the current warmth of the waters in the Arctic. In the summer of 2007, Arctic Ocean surface temperatures hit new maximums.

In waters just north of the Chukchi Sea (above Alaska and Eastern Siberia), sea-surface temperatures (SSTs) were 3.5C warmer than the historical average and 1.5C warmer than the historical maximum. SSTs of 4C were recorded.

This warming was probably the result of having increasing amounts of open water that readily absorb the sun’s rays, a phenomenon known as the ice-albedo feedback: less ice means less reflection and more absorption, leading to more warming and more melting.

“Water that is now circulating just 200 meters below the main ice pack is now significantly warmer than it was just five years ago,” said John Walsh of the University of Alaska, Fairbanks.

New research shows that carbon dioxide, one gas that traps heat in the atmosphere, can be captured as it leaves coal-burning power plants and then permanently sequestered in rock formations thousands of feet below the Earth’s surface.

How Much Time Is Left?
When asked how long the perennial ice might last, many researchers here shrugged their shoulders.

A report from the Intergovernmental Panel on Climate Change released in February predicts that the summer sea ice may disappear early in the next century.

More at National Snow and Ice Data Center, BBC News.

September 9, 2007, sea ice extent compared to animation of Septembers 1979 to 2006 


Dec 08 2007

Moore Foundation Funds Ambitious Project to Barcode an Entire Ecosystem

Moorea Tahiti

, Calif — In the middle of the South Pacific, about 12 miles west of Tahiti, is a tropical island that soon will emerge as a model ecosystem, thanks to the efforts of a U.S.-French research team led by University of California, Berkeley, biologists.

Moorea, home of the UC Berkeley Richard B. Gump South Pacific Research Station and France’s Centre de Recherches Insulaires et Observatoire de l’Environnement (CRIOBE), will be the site of an ambitious project to create a comprehensive inventory of all non-microbial life on the island. Supported by a new $5.2 million grant from the Gordon and Betty Moore Foundation, the Moorea Biocode Project over the next three years will send researchers climbing up jagged peaks, trekking through lush forests and diving down to coral reefs to sample the French Polynesian island’s animal and plant life.

“This is the first effort to catalog and barcode an entire tropical ecosystem, from the bottom of the ocean to the top of the mountains,” said George Roderick, UC Berkeley professor of environmental science, policy and management, curator of the campus’s Essig Museum of Entomology and co-principal investigator of the project.

“We’re constructing a library of genetic markers and physical identifiers for every species of plant, animal and fungi on the island, then making that database publicly available as a resource for ecologists and evolutionary biologists around the world,” he said. Roderick is a former director of the Gump Station, where the National Science Foundation has established one of its 26 Long Term Ecological Research sites (the Moorea Coral Reef LTER).

Moorea Lab

The work will expand upon a 2005 pilot biocode project at Moorea, also funded by the Moore Foundation, which tested the feasibility of such a large undertaking. That project was limited to genetic barcoding of the fishes, geckos and selected insects.

In the spirit of leaving no stone unturned, larvae and contents of animals’ guts will be fair game in the full project. “We’ll check the gut contents of a gecko, spider or fish to find out what it’s eating,” said Chris Meyer, who managed the pilot project while he was a researcher at UC Berkeley.

There are an estimated 5,000 plant, animal and fungal species on Moorea, although that number may change as cryptic communities and organisms are sampled and genetic markers reveal novel species. “I’d be disappointed if we don’t hit at least 10,000 species,” said Meyer.

The number of species on the 51-square-mile island of Moorea is small compared with that on larger islands and continents. In California, for example, the number of insect species alone tops 30,000. Yet, the researchers say Moorea provides the right balance of being small enough to be studied manageably while being sufficiently complex to reliably serve as a microcosm of the challenges faced in larger ecosystems.

Moorea Mountain

At the end of the three-year project, the Moorea Biocode Project will have sequenced a whole tropical ecosystem. “Like the Human Genome Project, however, this unprecedented accomplishment is, in some ways, merely a necessary first step,” said Davies. “Its goal is to accelerate progress on the larger questions: how to maintain a healthy ecosystem and what to do when things go wrong.” More at UC Berkeley, Berkeley.edu/Biocode. Photo Credits: UC Berkeley.

Cataloging an ecosystem
UC Berkeley biologist George Roderick talks about working on the South Pacific island of Moorea and an ambitious project to create a genetic inventory of all non-microbial life in the island’s ecosystem. (2:06 min. Flash video)


Dec 07 2007

Nanotube-producing Bacteria Show Manufacturing Promise

Nanotube-producing Bacteria Show Manufacturing Promise

Nanotubes may have high-tech applications, study involving UCR engineers reports.

RIVERSIDE, Calif — Dec 07, ‘07 — Two engineers at the University of California, Riverside are part of a binational team that has found semiconducting nanotubes produced by living bacteria – a discovery that could help in the creation of a new generation of nanoelectronic devices.

The research team believes this is the first time nanotubes have been shown to be produced by biological rather than chemical means. It opens the door to the possibility of cheaper and more environmentally friendly manufacture of electronic materials.

Study results appear in today’s issue of the early edition of the Proceedings of the National Academy of Sciences.

The team, including Nosang V. Myung, associate professor of chemical and environmental engineering in the Bourns College of Engineering, and his postdoctoral researcher Bongyoung Yoo, found the bacterium Shewanella facilitates the formation of arsenic-sulfide nanotubes that have unique physical and chemical properties not produced by chemical agents.

“We have shown that a jar with a bug in it can create potentially useful nanostructures,” Myung said. “Nanotubes are of particular interest in materials science because the useful properties of a substance can be finely tuned according to the diameter and the thickness of the tubes.”

The whole realm of electronic devices which power our world, from computers to solar cells, today depend on chemical manufacturing processes which use tremendous energy, and leave behind toxic metals and chemicals. Myung said a growing movement in science and engineering is looking for ways to produce semiconductors in more ecologically friendly ways.

Two members of the research team, Hor-Gil Hur and Ji-Hoon Lee from Gwangju Institute of Science and Technology (GIST), Korea, first discovered something unexpected happening when they attempted to remediate arsenic contamination using the metal-reducing bacterium Shewanella. Myung, who specializes in electro-chemical material synthesis and device fabrication, was able to characterize the resulting nano-material.

The photoactive arsenic-sulfide nanotubes produced by the bacteria behave as metals with electrical and photoconductive properties. The researchers report that these properties may also provide novel functionality for the next generation of semiconductors in nano- and opto-electronic devices.

In a process that is not yet fully understood, the Shewanella bacterium secretes polysacarides that seem to produce the template for the arsenic sulfide nanotubes, Myung explained. The practical significance of this technique would be much greater if a bacterial species were identified that could produce nanotubes of cadmium sulfide or other superior semiconductor materials, he added.

“This is just a first step that points the way to future investigation,” he said. “Each species of Shewanella might have individual implications for manufacturing properties.” More at University of California, Riverside.


Dec 06 2007

Intel Founder Gordon Moore Commits $200 Million to Build World’s Largest Telescope

Tag: Caltech, Intel, Science, Space, TechLuver, Telescope, UC, UniversitiesJack @ 3:25 PM

Intel Founder Gordon Moore Commits $200 Million to Build World’s Largest TelescopeThirty Meter Telescope: World’s Largest Telescope: Photo Credit: CaltechPASADENA, Calif — Dec 06, ‘07 –  The California Institute of Technology and the University of California have received a $200 million commitment over nine years from the Gordon and Betty Moore Foundation toward the further development and construction of the Thirty-Meter Telescope (TMT). Funding under this commitment will be shared equally between the two universities, with matching gifts from the two institutions expected to bring the total to $300 million. When built, TMT will be the largest telescope in the world.

The telescope design is being developed by a U.S.-Canadian team that includes the California Institute of Technology, the University of California, and the Association of Canadian Universities for Research in Astronomy (ACURA), with completion of the design development expected by March 2009.

With the TMT, astronomers will be able to locate and analyze the light from the first stellar systems born soon after the Big Bang, determine the physical processes governing the formation and evolution of galaxies like our own Milky Way, study planet formation around nearby stars, and make observations that test the fundamental laws of physics. However, it is the unexpected discoveries that TMT will make that will likely be the most exciting.

TMT will consist of a primary mirror with 492 individual 1.45-meter segments that together measure 30 meters in diameter, providing more than eight times the collecting area of the current largest telescope. All segments will be under precision computer control so that they will work together as a single mirror. This revolutionary technology was developed for the 10-meter mirrors in the two Keck telescopes in Hawaii.

The TMT will not only be the largest optical-infrared telescope in the world, but it will also be at the forefront of technology in virtually every aspect of its design. Adaptive optics (AO) will allow the TMT to achieve a resolution superior to that of the Hubble Space Telescope.

The TMT AO system will use six laser beams to create six luminous spots in a layer of sodium atoms high in Earth’s upper atmosphere. These bright artificial stars serve as references for measuring the turbulence in the atmosphere, allowing the AO system to compensate for blurring of starlight by Earth’s fluctuating atmosphere. This technology was pioneered at the Lick Observatory 3-meter telescope and has been developed further at the Palomar 5-meter and Keck 10-meter telescopes. More at Caltech.


Dec 05 2007

Herbal Extract Found to Increase Lifespan

Rhodiola_Rosea: Herbal Extract Found to Increase Lifespan: Photo Credit: University of California, IrvineIRVINE, Calif — Dec 05, ‘07 — The herbal extract of a yellow-flowered mountain plant indigenous to the Arctic regions of Europe and Asia increased the lifespan of fruit fly populations, according to a University of California, Irvine study.

Flies that ate a diet rich with Rhodiola rosea, an herbal supplement long used for its purported stress-relief effects, lived on an average of 10 percent longer than fly groups that didn’t eat the herb. Study results appear in the online version of Rejuvenation Research.

Mahtab Jafari, a professor of pharmaceutical sciences and study leader, University of California, Irvine“Although this study does not present clinical evidence that Rhodiola can extend human life, the finding that it does extend the lifespan of a model organism, combined with its known health benefits in humans, make this herb a promising candidate for further anti-aging research,” said Mahtab Jafari, a professor of pharmaceutical sciences and study leader. “Our results reveal that Rhodiola is worthy of continued study, and we are now investigating why this herb works to increase lifespan.”

In their study, the UC Irvine researchers fed adult fruit fly populations diets supplemented at different dose levels with four herbs known for their anti-aging properties. The herbs were mixed into a yeast paste, which adult flies ate for the duration of their lives. Three of the herbs – known by their Chinese names as Lu Duo Wei, Bu Zhong Yi Qi Tang and San Zhi Pian – had no effect on fruit fly longevity, while Rhodiola was found to significantly reduce mortality. On average, Rhodiola increased survival 3.5 days in males and 3.2 days in females.

Rhodiola rosea, also known as the golden root, grows in cold climates at high altitudes and has been used by Scandinavians and Russians for centuries for its anti-stress qualities. The herb is thought to have anti-oxidative properties and has been widely studied.

Soviet researchers have been studying Rhodiola since the 1940s on athletes and cosmonauts, finding that the herb boosts the body’s response to stress. And earlier this year, a Nordic Journal of Psychiatry study on people with mild-to-moderate depression showed that patients taking a Rhodiola extract called SHR-5 reported fewer symptoms of depression than did those who took a placebo.

Jafari said she is evaluating the molecular mechanism of Rhodiola by measuring its impact on energy metabolism, oxidative stress and anti-oxidant defenses in fruit flies. She is also beginning studies in mice and in mouse and human cell cultures. These latter studies should help understand the benefits of Rhodiola seen in human trials. More at University of California, Irvine.


Dec 05 2007

A Really Inconvenient Truth: Divorce is Not Green, It Hurts the Planet Too

A Really Inconvenient Truth: Divorce is Not Green, It Hurts the Planet TooEAST LANSING, Mich — Dec 05, ‘07 — The data are in. Divorce is bad for the environment.

A novel study that links divorce with the environment shows a global trend of soaring divorce rates has created more households with fewer people, has taken up more space and has gobbled up more energy and water. The findings of Jianguo “Jack” Liu and Eunice Yu at Michigan State University are published in this week’s online edition of the Proceedings of the National Academy of Sciences.

A statistical remedy: Fall back in love. Cohabitation means less urban sprawl and softens the environmental hit.

“Not only the United States, but also other countries, including developing countries such as China and places with strict religious policies regarding divorce, are having more divorced households,” Liu said. “The consequent increases in consumption of water and energy and using more space are being seen everywhere.”

Liu and his research assistant Yu started with the obvious – that divorce rates across the globe are on the rise. Housing units, even if they now have few people in them, require resources to construct them and take up space. They require fuel to heat and cool. A refrigerator uses roughly the same amount of energy whether it belongs to a family of four or a family of two.

When they calculated the cost in terms of increased utilities and unused housing space per capita, they discovered that divorce tosses out economy of scale. Among the findings:

* In the United States alone in 2005, divorced households used 73 billion kilowatt-hours of electricity and 627 billion gallons of water that could have been saved had household size remained the same as that of married households. Thirty-eight million extra rooms were needed with associated costs for heating and lighting.

* In the United States and 11 other countries such as Brazil, Costa Rica, Ecuador, Greece, Mexico and South Africa between 1998 and 2002, if divorced households had combined to have the same average household size as married households, there could have been 7.4 million fewer households in these countries.

* The numbers of divorced households in these countries ranged from 40,000 in Costa Rica to almost 16 million in the United States around 2000.

* The number of rooms per person in divorced households was 33 percent to 95 percent greater than in married households.

To track what happens when divorced people returned to married life, the study compared married households with households that had weathered marriage, divorce and remarriage. The results: The environmental footprint shrunk back to that of consistently married households.

This new work also acknowledges that divorce is not the only lifestyle trend changing family living structures – the demise of multigenerational households and people remaining single longer are examples.

“Solutions are beyond a single idea,” Liu said. “Consider the production of biofuel. Biofuel is made from plants, which also require water and space. We’re showing divorce has significant competition for that water and space. On the other hand, more divorce demands more energy. This creates a challenging dilemma and requires more creative solutions.”

The research was funded by the National Science Foundation, the National Institutes of Health and the Michigan Agricultural Experiment Station. More at Michigan State University.


Dec 04 2007

National Geographic Launches ‘Dino Central Park’ Ahead of Dino Death Trap

National Geographic Launches ‘Dino Central Park’ Ahead of Dino Death TrapNational Geographic Launches ‘Dino Central Park’ Ahead of Dino Death TrapNational Geographic Launches ‘Dino Central Park’ Ahead of Dino Death Trap

Dec 04, ‘07 — In support of its upcoming special, Dino Death Trap, National Geographic has launched Dino Central Park.  Featuring a hidden “webcam” in Central Park , the website allows users to scare the pants off of unsuspecting New Yorkers walking through the park by controlling a virtual Dino hidden in the bushes.

Dino Death Trap , premiering Sunday December 9th at 8:00 pm, digs up brand new species of dinosaurs from a lost age of the early Jurassic. Be there and join National Geographic as they travel to western China , deep in the dry and desolate Junggar Basin , when the graves never-before-seen Dinos are uncovered.

Some scientists are calling it “The Pit of Death”, others, “Dinosaur Pompeii”.  Envision dinosaur corpses stacked one on top of each other, piled four and five high.  A bizarre T. Rex ancestor, a Triceratops ancestor, an ancient Crocodilian, and nearly 40 more different species dating back 160 million years ago are uncovered in front of National Geographic cameras.

On Dino Death Trap you can follow a team of paleontologists, led by Dr. Jim Clark, of George Washington University , and Dr. Xu Xing, of the Chinese Academy of Sciences as they unearth answers to a virtual black hole in dinosaur evolution.  Watch as the bones are examined, reconstructed and brought back to life, using high resolution CGI, and slowly probe the mystery of who these dinosaurs were, how they died and what they can tell us about the Lost Age of the Dinosaurs.

Want more Dinosaurs?  From DinoCentralPark, head over to NGCDinos where you’ll find 3-D Dino renderings, a fossil hunt game, a Dino mummy timeline, and six video previews of the show.

Dino Death Trap Previews, Dino Central park, NGCDinos. [ Thanks ‘Brian Ries’ ]


Dec 03 2007

Montclair State University in NJ Mandates GPS Cell Phones

Montclair State University in NJ Mandates GPS Cell PhonesMontclair, NJ — Dec 03, ‘07 — It was after 1 a.m. on a Sunday when college freshman Amanda Phillips arrived at the train station. She was nervous about walking alone in the dark to her dorm at Montclair State University.

So Phillips activated a GPS tracking device on her school-issued cell phone that would instantly alert campus police to her whereabouts if she didn’t turn it off in 20 minutes. After a five-minute walk, she safely reached her dorm room, locked the door behind her and turned off the timer.

“I think this is a great idea. It makes me feel a lot safer. And it’s not even that expensive,” said Phillips, an 18-year-old from Delaware.

Had she not turned the device off, an alarm would have sounded at the campus police station, and a computer screen would have displayed a dot with her location, along with her photo and other personal details.

College students at Montclair State University are all talking about a new requirement that will require students to have a cell phone.

Montclair is one of the first schools in the U.S. to use GPS tracking devices, which along with other security technology are increasingly being adopted on campuses in the wake of the Virginia Tech massacre last spring.

Students can use the timer, or, in an emergency, activate the GPS technology to instantly alert police.

The cost: $420 a year for a base plan which is bundled into the tuition bill.

It includes just 50 peak voice minutes a month, but unlimited text messaging to any carrier, unlimited campus-based data usage, and student activated emergency GPS tracking.

“What it does is allow students to have an extra pair or group of people watching over them when they’re going from one location to another,” Montclair Police Department Chief Paul Cell said.

The positive impact is already being felt across campus.

The university contracted with the New York-based upstart Rave Wireless for the safety technology and Sprint for the cell phone service. Montclair State said it is not making money on the deal. It said the total cost is around $2 million per year — almost exactly what the school collects from students to fund it.

Sprint added cell towers so that virtually every inch of the campus gets service.

Raju Rishi, co-founder of Rave, said Montclair State was the first to use the safety feature, called Rave Guardian. A half-dozen other schools, including nearby Fairleigh Dickinson University and the University of North Carolina, now use similar systems, Rishi said.

Rishi said campus police are not monitoring the movements of students who don’t turn on the GPS feature. “There’s no Big Brother,” Rishi said. “You need a subpoena to locate somebody against their will.” More at AP, WCBSTV.com


Dec 03 2007

Chimp Shows Extraordinary Memory, Beats Students at Computer Game

Chimp Shows Extraordinary Memory, Beats Students at Computer GameDr_Tetsuro_Matsuzawa_of_Kyoto_University_with_Chimps_Ai_AyumaDec 03, ‘07 — Chimpanzees have an extraordinary photographic memory that is far superior to ours, research suggests. Young chimps outperformed university students in memory tests devised by Japanese scientists.

The research, published in Current Biology, suggests we may have under-estimated the intelligence of our closest living relatives. Until now, it had always been assumed that chimps could not match humans in memory and other mental skills.

“There are still many people, including many biologists, who believe that humans are superior to chimpanzees in all cognitive functions,” said lead researcher  of Kyoto University.

“No one can imagine that chimpanzees - young chimpanzees at the age of 5 - have a better performance in a memory task than humans,” he said in a statement.

Matsuzawa, a pioneer in studying the mental abilities of chimps, said even he was surprised. He and colleague Sana Inoue report the results in Tuesday’s issue of the journal Current Biology.

One memory test included three 5-year-old chimps who’d been taught the order of Arabic numerals 1 through 9, and a dozen human volunteers.

They saw nine numbers displayed on a computer screen. When they touched the first number, the other eight turned into white squares. The test was to touch all these squares in the order of the numbers that used to be there.

Results showed that the chimps, while no more accurate than the people, could do this faster. One chimp, Ayumu, did the best. Researchers included him and nine college students in a second test.

This time, five numbers flashed on the screen only briefly before they were replaced by white squares. The challenge, again, was to touch these squares in the proper sequence.

When the numbers were displayed for about seven-tenths of a second, Ayumu and the college students were both able to do this correctly about 80 percent of the time.

But when the numbers were displayed for just four-tenths or two-tenths of a second, the chimp was the champ. The briefer of those times is too short to allow a look around the screen, and in those tests Ayumu still scored about 80 percent, while humans plunged to 40 percent.

That indicates Ayumu was better at taking in the whole pattern of numbers at a glance, the researchers wrote.

Dr Lisa Parr, who works with chimps at the Yerkes Primate Center at Emory University in Atlanta, US, described the research as “ground-breaking”. She said their importance of these primates for understanding the skills necessary for the evolution of modern humans was unparalleled.

“They are our closest living relatives and thus are in a unique position to inform us about our evolutionary heritage,” said Dr Parr.

“These studies tell us that elaborate short-term memory skills may have had a much more salient function in early humans than is present in modern humans, perhaps due to our increasing reliance on language-based memory skills.” More at BBC News.


Dec 03 2007

Mummified Dinosaur Astonishes Scientists

Tag: BBC, Boeing, Nature, Research, Science, Study, TechLuver, UniversitiesJack @ 7:25 AM

Dakota, a 67-million-year-old “dino mummy” unveiled today by a British paleontologist, is seen here in an artist’s rendering.The scales are still visible on the fossilised skinDec 03, ‘07 — Fossil hunters have uncovered the remains of a dinosaur that has much of its soft tissue still intact. Skin, muscle, tendons and other tissue that rarely survive fossilisation have all been preserved in the specimen unearthed in North Dakota, US.

The 67 million-year-old dinosaur is one of the duck-billed hadrosaur group. The preservation allowed scientists to estimate that it was more muscular than thought, perhaps giving it the ability to outrun predators like T. rex.

While they call it a mummy, the dinosaur is not really preserved like King Tut was. The dinosaur body has been fossilized into stone. Unlike the collections of bones found in museums, this hadrosaur came complete with skin, ligaments, tendons and possibly some internal organs, according to researchers.

The study is not yet complete, but scientists have concluded that Hadrosaurs were bigger - 3 1/2 tons and up to 40 feet long - and stronger than had been known, were quick and flexible and had skin with scales that may have been striped.

“Oh, the skin is wonderful,” paleontologist Phillip Manning of Manchester University in England rhapsodized, admitting to a “glazed look in my eye.”

“It’s unbelievable when you look at it for the first time,” he said in a telephone interview. “There is depth and structure to the skin. The level of detail expressed in the skin is just breathtaking.”

The fossil was found in 1999 and is now nicknamed Dakota. It is being analysed in the world’s largest CT scanner, operated by the Boeing corporation.

The machine usually is used for space shuttle engines and other large objects. Researchers hope the technology will help them learn more about the fossilised insides of the creature.

The reptile had no chest cavity, suggesting it had been partially eaten by predators before being “mummified” in unusual conditions: acidic, waterlogged sediments collected around the dinosaur, triggering the rapid deposit of minerals and trapping organic molecules before they decayed.

Dakota was discovered by Tyler Lyson, then a teenager who liked hunting for fossils on his family ranch. Lyson, who is currently working on his doctorate degree in paleontology at Yale University, founded the Marmarth Research Foundation, an organization dedicated to the excavation, preservation and study of dinosaurs. More at National Geographic, BBC News.


Nov 29 2007

Embryonic Star Captured With Jets Flaring

Click on the image for details: Baby_Picture_of_our_Solar_SystemClick on the image for details: Spinning Top StarNov 29, ‘07 — A developing star wrapped in a black cocoon of dust is seen sprouting giant jets in a new image from NASA’s Spitzer Space Telescope.

The stellar portrait, seen in infrared light, offers the first glimpse at a very early stage in the life of an embryonic sun-like star — a time when the star’s natal envelope is beginning to flatten and collapse, and streams of gas are escaping. The observations will ultimately help astronomers better understand how stars and their planets form.

“This is the first time we’ve clearly seen a flattened envelope around a forming star,” said Leslie Looney of the University of Illinois at Urbana-Champaign, lead author of a study about the star, called L1157, appearing Dec. 1 in Astrophysical Journal Letters. “Some theories had predicted that envelopes flatten as they collapse onto their stars and surrounding planet-forming disks, but we hadn’t seen any strong evidence of this until now.”

Stars are born out of thick clouds, or envelopes, of gas and dust that condense and collapse inward. As a star grows and feeds off the envelope, it spins faster and faster like a twirling ice skater. A disk of planet-forming material begins to take shape in orbit around the star, and jets of gas shoot up from above and below the disk to relieve the star’s accumulating pressure. Eventually, the original envelope falls onto the spinning disk, and the jets slow to a stop.

The regions where all the action takes place are dark and dusty, letting little visible light escape. For example, the embryonic star L1157 appears black in visible-light views. Spitzer’s infrared view of the star, on the other hand, penetrates the dusty haze, giving us a rare look at what our own solar system might have looked like when it was very young.

The bipolar jets shooting away from L1157 are enormous; light itself would take about nine months to travel the length of one jet. The color white shows the hottest parts of the jets, with temperatures around 100 degrees Celsius (212 degrees Fahrenheit). Most of the material in the jets, seen in orange, is roughly zero degrees on the Celsius and Fahrenheit scales.

The flattened envelope around the fledgling star is perpendicular to the jets and appears deep black. This is because it is so thick with dust that even infrared light cannot escape. The envelope is big enough to engulf the equivalent of tens of thousands of mature solar systems similar to our own, while the planet-forming disk tucked inside cannot be seen in this photo – it is smaller than a pixel.

L1157 is located about 800 light-years away in the constellation Cepheus. It is roughly 10,000 years old, and, according to astronomers’ estimates, will ignite to become a full-fledged star about the mass of our sun in a million years or so.

“Taking baby pictures of stars is not easy to do,” said Looney. “Now that we have a good picture, we can begin to ask questions about whether this star system and its potential planets will grow up to become like ours.”

Other authors of this study include John J. Tobin of the University of Michigan, Ann Arbor, and Woojin Kwan of the University of Illinois.

More at NASA.


Nov 29 2007

Organic ‘Building Blocks’ Discovered in Titan’s Atmosphere

Tag: ESA, NASA, Research, Science, Space, TechLuver, UniversitiesJack @ 11:36 AM

Click for Image Details: Organic ‘Building Blocks’ Discovered in Titan’s AtmosphereNov 29, ‘07 — Scientists analyzing data gathered by Cassini have confirmed the presence of heavy negative ions in the upper regions of Titan’s atmosphere. These particles may act as building blocks for more complicated organic molecules.

The discovery was completely unexpected because of the chemical composition of the atmosphere (which lacks oxygen - responsible for forming negative ions in the lower ionosphere of the Earth - and mainly consists of nitrogen and methane). The observation has now been verified on 16 different encounters.

Prof Andrew Coates, researcher at University College London’s Mullard Space Science Laboratory and lead author of the paper, says: “Cassini’s electron spectrometer has enabled us to detect negative ions which have 10 000 times the mass of hydrogen. Additional rings of carbon can build up on these ions, forming molecules called polycyclic aromatic hydrocarbons, which may act as a basis for the earliest forms of life.

Coates added, “Their existence poses questions about the processes involved in atmospheric chemistry and aerosol formation and we now think it most likely that these negative ions form in the upper atmosphere before moving closer to the surface, where they probably form the mist which shrouds the planet and which has hidden its secrets from us in the past. It was this mist which stopped the Voyager mission from examining Titan more closely in 1980 and was one of the reasons that Cassini was launched.”

The new paper builds on work published in Science on 11 May where the team found smaller tholins, up to 8000 times the mass of hydrogen, forming away from the surface of Titan.

Dr Hunter Waite of the South West Research Institute in Texas and author of the earlier study, said: “Tholins are very large, complex, organic molecules thought to include chemical precursors to life. Understanding how they form could provide valuable insight into the origin of life in the solar system.”

The findings, authored by A. Coates, F. Crary, G. Lewis, D. Young, J. Waite Jr. and E. Sittler Jr., published yesterday, 28 November, in the Geophysical Research Letters appear in ‘Discovery of heavy negative ions in Titan’s ionosphere’. More at ESA.


Nov 25 2007

A Wiring Diagram of the Brain

Analyzing axons: Scientists are developing new ways to study the tangled web of neurons in the brain.Emily Singer at TechnologyReview writes an in-depth article on  The emerging field of connectomics could help researchers decode the brain’s approach to information processing.

“New technologies that allow scientists to trace the fine wiring of the brain more accurately than ever before could soon generate a complete wiring diagram–including every tiny fiber and miniscule connection–of a piece of brain. Dubbed connectomics, these maps could uncover how neural networks perform their precise functions in the brain, and they could shed light on disorders thought to originate from faulty wiring, such as autism and schizophrenia.

“The brain is essentially a computer that wires itself up during development and can rewire itself,” says Sebastian Seung, a computational neuroscientist at MIT. “If we have a wiring diagram of the brain, that could help us understand how it works.” For example, scientists previously identified the part of the songbird’s brain that is important in the birds’ ability to generate songs. Seung would ultimately like to develop a wiring diagram of this structure in order to elucidate the features underlying its unique capability.

Only one organism’s wiring diagram currently exists: that of the microscopic worm C. elegans. Despite containing a mere 302 neurons, the C. elegans mapping effort took more than a decade to complete, in the 1970s. It has been an invaluable research resource and earned its creators a Nobel Prize.

With an estimated 100 billion neurons and 100 trillion synapses in the human brain, creating an all-encompassing map of even a small chunk is a daunting task. Using standard methods, it would take roughly three billion person years to generate the wiring diagram of a single cortical column, a narrow functional unit of neurons in the cortex, estimates Winfried Denk, a neuroscientist at the Max Planck Institute for Medical Research in Heidelberg, Germany.

Denk, Seung, and their collaborators are now developing sensitive new imaging techniques and machine-learning algorithms to automate the construction process. They have already generated a partial wiring diagram of part of the rabbit retina. But they’ll need to make their technique a million times faster to finally bring larger maps–like that of a cortical column–into the realm of reality.

Previous efforts to map the wiring of the brain have focused on larger anatomical features, such as the thick wiring tracts that connect different parts of the brain, or on the paths of single neurons, stained a particular color to distinguish them from their tangled multitude of neighbors.

But to truly understand how a network of neurons can perform a particular function, scientists need a new kind of map. “A lot of properties of brain function are at the level of the circuit–information is being integrated, processed, extracted,” says Elly Nedivi, a neuroscientist at MIT who is not involved with the research. “To understand what that means, you need to be able to see who connects to who.”

Denk and his colleagues developed a new technique to make more fine-scaled wiring maps using electron microscopy. Starting with a small block of brain tissue, the researchers bounce electrons off the top of the block to generate a cross-sectional picture of the nerve fibers in that slice. They then take a very thin–30-nanometer–slice off the top of the block and repeat the process. Scientists go through the images slice by slice to trace the path of each nerve fiber. “Repeat this [process] thousands of times, and you can make your way through maybe the whole fly brain,” says Denk.

Seung and Denk aim to dramatically speed up the tracing process, which takes a single graduate student weeks to complete, with automated machine-learning algorithms. The researchers use data from a manually generated wiring diagram to train an artificial neural network to emulate the human tracing process. They can then use the resulting algorithm to analyze new chunks of brain tissue. To date, they’ve been able to speed the process about one hundred- to one thousand-fold.

The researchers presented their initial findings to an awed crowd at the Society for Neurosciences meeting in San Diego earlier this month. They showed the three-dimensional reconstruction of part of the rabbit retina called the inner plexiform layer, which is a piece of neural tissue at the back of the eye that senses light and sends visual information to the brain. (See a movie of the reconstruction here.) “But we need to improve 106-fold or more,” says Denk, who estimates that this would shrink the three billion person years it would take to trace a cortical column down to about two years. “I’m confident in the end that we will be able to do it,” he says. “But I don’t know how long it will take us–if we’re lucky, maybe a year or so.”

Earlier this month, scientists at Harvard described a new method of tracing neurons in the living brain by labeling them with up to a hundred different colors. (See “The Technicolor Brain.”) “We’re starting to think about wiring diagrams as being fundamental,” says Jeff Lichtman, one of the researchers who developed the technique.

Researchers say that the two approaches will likely be complementary, allowing scientists to look at neural circuits of different dimensions. Eventually, Seung aims to generate maps of the complete fly connectome, as well as partial wiring diagrams of interesting locations in larger brains, such as the hippocampus, olfactory bulb, and retina.

Just exactly how much light these maps will shed on the brain is still somewhat controversial. “Just knowing the [wiring] data won’t take us far if we don’t put it in the framework of processing and transferring data in the brain,” says David van Essen, a neuroscientist at Washington University, in St. Louis, and president of the Society for Neurosciences. Seung and others eventually hope to generate maps that incorporate the biochemical and physiological properties of various cells into the wiring diagrams.” TechnologyReview.


Nov 25 2007

Einstein-Predicted Gravitational Waves May Change Perceptions of the Universe

Tag: Research, Science, Space, Study, TechLuver, UniversitiesJack @ 5:07 AM

Albert Einstein: Einstein-Predicted Gravitational Waves May Change Perceptions of the UniverseThe Laser Interferometer Gravitational-wave Observatory, or LIGO: Einstein’s Predicted Gravitational Waves May Change Perceptions of the UniverseResearchers at the University of Wisconsin Milwaukee are leading a new study involving 500 scientists worldwide to find, analyze, and prove the existence of gravitational waves in order to learn even more about our universe.

Gravitational waves were predicted by Albert Einstein, but so far, it has not been proven that they exist.

A new window on the universe

“Galileo was the first person to use the telescope to view the cosmos,” says Brady, a UWM professor of physics. “His observations with the new technology led to the discovery of moons orbiting Jupiter and lent support to the heliocentric model of the solar system.”

Just such an opportunity exists today with a unique observatory that is scanning the skies, searching for one of Einstein’s greatest predictions – gravitational waves.

Gravitational waves are produced when massive objects in space move violently. The waves carry the imprint of the events that cause them. Scientists already have indirect evidence that gravitational waves exist, but have not directly detected them.

UWM researchers, backed by considerable funding from the National Science Foundation, are taking a leadership role in the quest.

It is an epic undertaking involving about 500 scientists worldwide, including Brady and other members of UWM’s Center for Cosmology and Gravitation: associate professors Alan Wiseman and Jolien Creighton, and assistant professor Xavier Siemens.

Two UWM adjunct physicists, who work at the Max Planck Institute in Germany, also are involved – former UWM professor Bruce Allen and scientist Maria Alessandra Papa.

“It’s an unimaginable opportunity to be on the forefront of scientific discovery,” says Creighton.

The Laser Interferometer Gravitational-wave Observatory, or LIGO, consists of detectors at two U.S. sites managed by the California Institute of Technology (Caltech) and Massachusetts Institute of Technology (MIT).

UWM’s physicists are analyzing the data generated by the LIGO facilities.

The project is supported with a sizable investment of grant money from both federal and UWM sources.

Last year, UWM’s LIGO group brought in $3 million in grant funding. Since 1999, UWM has received more than $9 million for the project, with much of it going toward a supercomputer called Nemo that operates unobtrusively on the second floor of the Physics Building.

Stretching and squeezing

The LIGO observatories use lasers to accurately monitor the distance between a central station and mirrors suspended three miles away along perpendicular arms. When a gravitational wave, a traveling ripple in space-time, passes by, the mirror in one arm will move closer to the central station, while the other mirror will move away.

The change in distance caused by stretching and squeezing is what LIGO is designed to measure, says Wiseman.

Those changes will be inconceivably tiny. LIGO can record distortions at a scale so small, it is comparable in distance to a thousandth of the size of an atomic nucleus.

LIGO records a series of numbers – lots of them – and feeds them to several supercomputer clusters around the country, including UWM’s Nemo cluster.

Think of a modern hard disk on a desktop computer, which stores about 100 gigabytes. LIGO fills up about 10 of those at Nemo in a single day, says Brady.

The computer’s job is to sort out the numerical patterns representing gravitational waves buried in ambient noise produced by lots of other vibrations – from internal vibrations of the equipment itself, to magnetic fluctuations from lightning storms, to seismic vibrations from trains rolling along the tracks a few miles from the observatory, or from earthquakes on the other side of the world.

“There are thousands or even millions of different signals that could be emitted from space,” says Wiseman. “So you have to take each segment of data individually. That turns out to be a formidable computational problem.”

Nemo performs many billions of calculations per second in its search for these signals.

Space sounds

The strings of numbers from LIGO are like tracks on a compact disk, says Brady. That means, once detected, gravitational-wave signals can be converted into sound.

In fact, scientists have already simulated, based on mathematical predictions, what certain events in space will sound like.

When two black holes are merging, for example, you might expect to hear a “chirp” that represents the spiraling together of the black holes just before they collide. “The spiral can go on for tens of thousands of years,” says Brady. “The sound is the identifying signal of the last few seconds of the process!”

Those analyzing the data from space could actually listen to the data. Instead, scientists look for the signals using computers like Nemo.

To augment the computing capacity, UWM is hosting a way for anyone with a computer and a high-speed Internet connection to join the astrophysical treasure hunt. Called “Einstein@Home, the program borrows computer power available when participants are not using it, and pool those resources to aid in filtering the massive amounts of data from LIGO.

Possible secrets

Scientists concede that the current LIGO facilities will need to be improved to increase the chances of detecting gravitational waves. More NSF funding to do that is requested in the 2009 U.S. budget currently winding its way through the approval process.

For now, the best hope is to detect events relatively close to Earth.

So what is the likelihood of success”

“The events we are looking for may only happen once every million years in our galaxy,” says Wiseman, “but if your instrument is sensitive enough to see such events in, say, one million galaxies, then the probability of detecting something is much larger.”

Gravitational waves may hold secrets to the nature of black holes, the unknown properties of nuclear material, and maybe even how the universe began.

“We’ve only been able to find out about the universe since it became cool,” says Siemens. “But with gravitational waves, we’ll see the universe when it was much younger – and hotter.”

But then again, scientists don’t really know.

“I think we’re in for a surprise,” says Siemens. “We have all these ideas about what we think we will find, but it could be something completely different.” UWM.


Nov 23 2007

IceCube Neutrino Detector Set to Take Snaps of Earth’s Core

Tag: Science, TechLuver, Telescope, UniversitiesJack @ 3:08 PM

A proposed high-energy neutrino detector created by instrumenting a cubic kilometer of ice under the South Pole stationThe first neutrino event observed by IceCube. A neutrino interaction below the detector produced a muon which is going nearly vertically upwardIceCube Neutrino Detector Set to Take Snaps of Earth’s CoreIceCube Neutrino Detector Set to Take Snaps of Earth’s CoreIceCube Neutrino Detector Set to Take Snaps of Earth’s CoreIceCube is a telescope under construction at the South Pole at the US Amundsen-Scott station.

It is an unusual telescope in many respects.  It is buried a mile down in the Antarctic ice sheet, rather than situated at the surface.

IceCube looks down, into (and through) the earth, rather than up into the sky.  And finally, the “light” seen by this telescope is composed of individual fundamental particles called neutrinos.  In a real sense, IceCube is opening a new window on the universe and will map the neutrino sky.

Upon completion in 2010, IceCube will consist of over 4000 sensors located in a volume of about one cubic kilometer of highly transparent ice situated between 1500 and 2500 meters below the surface.

These sensors will detect the optical light emitted by other fast-moving electrically-charged particles (electrons, muons) moving upward, each of which is the result of a collision with a high-energy neutrino that penetrated the earth. IceCube will determine the directions from which the neutrinos, which have no electrical charge and practically no mass, came to us and how much energy each carried. (See the animation)

This is a new kind of astronomy, one that we hope will tell us new things about our universe.  For example, one of the goals of high-energy neutrino astronomy is to discover the origin of the extremely high-energy cosmic rays that bombard our earth.  We believe we can use neutrinos to identify the sites in the distant universe where these cosmic rays are produced.

IceCube is being built by an international collaboration of scientists and engineers.  The US funding comes from the National Science Foundation and the lead institution is the University of Wisconsin-Madison.  Lawrence Berkeley National Laboratory is a member of this collaboration and has several key responsibilities in the scientific and technical effort surrounding IceCube and its predecessor, AMANDA (the Antarctic Muon And Neutrino Detector Array). More at IceCube.LBL.gov


Nov 21 2007

University of Bristol Researcher Finds Bigger than a Man Giant Fossil Sea Scorpion

University of Bristol Researcher Finds Bigger than a Man Giant Fossil Sea ScorpionUniversity of Bristol Researcher Markus Poschmann with the Giant Fossil Sea Scorpion ClawNov 21, ‘07 — The discovery of a giant fossilised claw from an ancient sea scorpion indicates that when alive it would have been about two-and-a-half meters long, much taller than the average man.

This find, from rocks 390 million years old, suggests that spiders, insects, crabs and similar creatures were much larger in the past than previously thought.

Dr Simon Braddy from the Department of Earth Sciences at the University of Bristol, co-author of an article about the find, said, ‘This is an amazing discovery. We have known for some time that the fossil record yields monster millipedes, super-sized scorpions, colossal cockroaches, and jumbo dragonflies, but we never realised, until now, just how big some of these ancient creepy-crawlies were.’

The research is published online today in the Royal Society’s journal Biology Letters. The claw was discovered by one of Dr Braddy’s co-authors, Markus Poschmann, in a quarry near Prüm in Germany.

Poschmann described finding the fossil: ” I was loosening pieces of rock with a hammer and chisel when I suddenly realised there was a dark patch of organic matter on a freshly removed slab. After some cleaning I could identify this as a small part of a large claw. Although I did not know if it was more complete or not, I decided to try and get it out. The pieces had to be cleaned separately, dried, and then glued back together. It was then put into a white plaster jacket to stabilise it.”

The claw is from a sea scorpion (eurypterid) Jaekelopterus rhenaniae that lived between 460 and 255 million years ago. It is 46 centimetres long, indicating that the sea scorpion to which it belonged was around 2.5 metres (8 feet) long – almost half a metre longer than previous estimates for these arthropods and the largest one ever to have evolved.

Eurypterids are believed to be the extinct aquatic ancestors of scorpions and possibly all arachnids.

Some geologists believe that giant arthropods evolved due to higher levels of oxygen in the atmosphere in the past. Others, that they evolved in an ‘arms race’ alongside their likely prey, the early armoured fish.

‘There is no simple single explanation’, explains Braddy. ‘It is more likely that some ancient arthropods were big because there was little competition from the vertebrates, as we see today. If the amount of oxygen in the atmosphere suddenly increased, it doesn’t mean all the bugs would get bigger.’ More at University of Bristol.


Nov 20 2007

Scientists Reprogram Skin Cells to Act Like Embryonic Stem Cells

Scientists Reprogram Skin Cells to Act Like Embryonic Stem CellsNov 20, ‘07 — Human skin cells can be reprogrammed to behave almost exactly like embryonic stem cells, a discovery that provides a road map for creating personalized biological repair kits without ethical strings attached, scientists reported today.

Two separate teams of scientists say they have transformed ordinary human skin cells into ones that look and act like embryonic stem cells.

Laboratory teams at universities in the United States and Japan Tuesday announced the breakthrough, which may someday produce the medical benefits of embryo cloning without political, scientific and ethical controversies.

Both teams used a retrovirus to transport four genes into the skin cells, producing ones that mimic embryonic stem cells.

The U.S. team reported its findings in the journal Science, and the Japanese scientists reported theirs in the journal Cell.

By activating a handful of dormant genes, the researchers were able to coax the cells to go backward in time to a point in embryonic development before they had committed to becoming facial skin. The rejuvenated cells were able to grow into all the main tissue types in the body, including muscle, gut, cartilage, neurons and heart cells.

Several key hurdles remain before the technique is ready for clinical use. The viruses employed to turn on the genes cause mutations that can lead to cancer, and one of the genes itself also has a tendency to cause tumors. But scientists said solutions to these problems were already in the works.

Stem cells are coveted for their ability to grow into any kind of cell, such as the insulin-secreting islet cells that diabetes patients need or the brain tissue that could treat stroke victims. Until now, the only source of such pluripotent cells was from the inner cell mass of an early stage embryo, and the only way to harvest them was by destroying the embryo.

The prospect of creating pluripotent cells from ordinary skin cells is attractive to religious and social conservatives who consider embryos a sacred form of human life.

It is also a more straightforward way to generate stem cell lines that are genetically matched to patients.

Just last week, cloning pioneer Ian Wilmut said he planned to shift his focus from nuclear transfer – the technology he used to produce Dolly the sheep in 1997 — to cellular reprogramming.

Shinya Yamanaka and his colleagues at Kyoto University spearheaded the reprogramming technique in mice. They dubbed their cells induced pluripotent stem cells, or iPS cells.

Yamanaka’s group used a retrovirus to turn on four genes that produce proteins — Oct4, Sox2, c-Myc and Klf4 — crucial for embryonic development. It took about 30 days for the cells to form colonies that resembled groups of embryonic stem cells.

The researchers grew the iPS cells in dishes and found they behaved almost exactly like embryonic stem cells. Under the right conditions, they became neural cells, or cardiac cells that beat in unison. When injected into mice, the iPS cells formed tumors containing a jumble of body parts.

Altogether, the researchers were able to create about 10 lines of iPS cells from each batch of 50,000 skin cells.


Nov 17 2007

Cloning Pioneer Prof Ian Wilmut Abandons “Therapeutic Cloning”, Looks into New Method

Tag: Cloning, Research, Science, Study, TechLuver, UK, UniversitiesJack @ 8:48 AM

Cloning Pioneer Prof Ian Wilmut Abandons “Therapeutic Cloning”, Looks into New MethodThe scientist who created Dolly the sheep, a breakthrough that provoked headlines around the world a decade ago, is to abandon the cloning technique he pioneered to create her.

Nov 17, ‘07 — Prof. Ian Wilmut, who led the team that created Dolly in 1996, told The Daily Telegraph that he is abandoning cloning to pursue a new technique that can create stem cells without an embryo.

Prof Wilmut’s decision to turn his back on “therapeutic cloning“, just days after US researchers announced a breakthrough in the cloning of primates, will send shockwaves through the scientific establishment.

He and his team made headlines around the world in 1997 when they unveiled Dolly, born July of the year before.

But now he has decided not to pursue a licence to clone human embryos, which he was awarded just two years ago, as part of a drive to find new treatments for the devastating degenerative condition,